Molecular Targets for Tumor Radiosensitization
نویسندگان
چکیده
منابع مشابه
Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature
Despite wide margins and high dose irradiation, unresectable malignant glioma (MG) is less responsive to radiation and is uniformly fatal. We previously found that cytosolic phospholipase A2 (cPLA(2)) is a molecular target for radiosensitizing cancer through the vascular endothelium. Autotaxin (ATX) and lysophosphatidic acid (LPA) receptors are downstream from cPLA(2) and highly expressed in MG...
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ژورنال
عنوان ژورنال: Chemical Reviews
سال: 2009
ISSN: 0009-2665,1520-6890
DOI: 10.1021/cr800504x